Un patch anti-transpiration mesure les niveaux de médicaments bipolaires pour éviter les surdoses

4334857

2025-07-26

Picture MUST credit: Mohammad Shafiqul Islam, Khan Lab, USC Viterbi School of Engineering A wearable sensor could vastly improve treatment and drug safety for millions of patients with bipolar disorder simply through sweat levels. The medication lithium is a highly effective treatment for bipolar disorder. But too high a dose can be toxic to patients, causing kidney damage, thyroid damage or even death, while too low a dose renders the treatment ineffective. The dose required varies between individuals based on body weight, diet and other physiological factors. Lithium levels in the blood need constant monitoring currently done by lab investigations of blood samples The wearable includes a skin-safe system to induce sweat without requiring physical exertion. In just minutes, the device collects data, which is transmitted directly to a smartphone app, allowing patients to track their lithium levels from the comfort of their own homes. It uses organic electrochemical transistors which are electronic devices that respond to atoms or molecules in liquid, converting them into readable electronic data. A team at the USA's University of Southern California created one of these devices using a novel material formulation tailored to detect lithium specifically. Picture supplied by JLPPA

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